9 Best Dog Toothpastes (2024 Reviews & Top Picks)

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Whether you have puppies, adult dogs, or senior dogs, brushing their teeth no matter what their age should be a part of their routine dog grooming and care. It is ideal to start brushing your pup’s teeth at a young age but it is never too late to start.

We recommend brushing your dog’s teeth daily or 1-2 times per week. Like many owners, you can resort to brushing your dog’s teeth at least a few times per week to avoid any periodontal issues. As an added bonus, you’ll also keep that stinky dog breath at bay!

Selecting the best dog toothpaste for your canine friend is crucial. It makes the teeth cleaning routine more enjoyable and easier. Always use toothpaste specifically designed for dogs that are pet-tested, animal-approved, and veterinarian recommended.

There’s a wide variety of dog toothpaste – from organic, vet-recommended, all-natural to toothpaste for bad breath. We’ve reviewed the best ones for your dogs and took into consideration the cleaning power, enzymatic formula, non-foaming agent, flavor, and palatability. 

Based on our research and review, the Vetoquinol Enzadent Enzymatic Toothpaste for Dogs is our best overall top pick in dog toothpaste. The highly palatable poultry flavor will convince your furry friends to get their teeth brushed and the enzymatic formula in the toothpaste helps to effectively remove plaque.


DogLeashPro’s PicksBrandRating
Best Overall – Top PickVetoquinol Enzadent Enzymatic Toothpaste for Dogs4.7
Runner UpVirbac C.E.T. Enzymatic Toothpaste4.5
Best BudgetSentry Petrodex Enzymatic Toothpaste For Dogs4.5
Best Vet Recommended Dog ToothpasteVet’s Best Dental Gel Toothpaste4.3
Best Organic Dog ToothpasteRADIUS USDA Organic Toothpaste 4.4
*Ratings are from Amazon at the time of publication and may change

Our Top Pick: Vetoquinol Enzadent Enzymatic Toothpaste for Dogs

The Vetoquinol Enzadent Enzymatic Toothpaste for Dogs is our top pick because the highly palatable poultry flavor will attract your four-legged friends to get their teeth brushed.

The Enzadent toothpaste includes triple enzyme formula that effectively removes plaque from teeth and polishes without foaming up. The non-foaming formula means the toothpaste is safe to swallow so there’s no need to rinse. Brushing your dog’s teeth will be a breeze!

With regular brushing, tooth decay and gum disease can be prevented and your dog’s teeth will be sparkling clean.

Vetoquinol Enzadent Enzymatic Toothpaste for Dogs Key Features:

  • Comes with 3 pack of 3.2 oz tubes
  • Palatable poultry flavor from real poultry extract
  • Enzymatic formula removes plaque and polishes dog’s teeth
  • Safe if swallowed
  • Does not foam and no need for rinsing

What customers are saying:  


  • Many dog owners said their vets recommended this toothpaste. After using it, their dogs’ teeth were nice and white with no plaque buildup.
  • Dogs love the poultry flavor of the toothpaste, which makes teeth cleaning easier because it’s more like a treat to them.
  • Some owners recommend the enzadent dog toothpaste because of its enzymatic formula, which works even after you stop brushing.
  • Dog owners have noticed the tartar in their dogs’ teeth has decreased.
  • Some dogs can’t wait to get their teeth brushed or would remind their human owners to brush their teeth.
  • Before bedtime, a few dogs would just sit there staring at their owners until they get their teeth brushed.


  • While dogs love the poultry flavor, one dog owner did not like the smell of it. But overall, the toothpaste does what it says it will do.

Our Runner Up Pick: Virbac C.E.T. Enzymatic Toothpaste

With both its palatable poultry flavor and enzymatic formula, our runner-up pick is the Virbac C.E.T. Enzymatic Toothpaste. The Virbac toothpaste comes in three flavors, including poultry, beef, and vanilla mint to suit your canines’ taste. They will enjoy the taste and would not mind getting their teeth cleaned.

Not only is the toothpaste flavorful, but also it contains enzymes that break down plaque and control tartar formation to keep your dogs’ teeth and gums healthy. The CET toothpaste has a natural antibacterial formula to help freshen their breath. Say bye to the stinky dog breath!

In addition, the toothpaste does not foam so it is safe if swallowed and does not require rinsing. Brushing their teeth will no longer be a chore!

Virbac C.E.T. Enzymatic Toothpaste Key Features:

  • Comes in 3 flavors: poultry, beef, and vanilla mint
  • Enzymatic formula to reduce plaque, control tartar formation, and freshen breath
  • Does not foam, no need for rinsing, and safe to swallow
  • Highly recommended by veterinary professionals
  • C.E.T. brand is an at-home pet dental care product for more than 30 years
  • Made in the USA

What customers are saying:  


  • Many dog owners said after one use of the Virbac toothpaste, their dogs have noticeably whiter teeth. After the second use, the black ring of buildup in the gum line slid right off without effort.
  • Some owners advised brushing the dogs’ teeth after they’ve exercised and are panting so it’s easy to keep their mouth wide open.
  • Dog owners said they’re glad they tried the CET toothpaste first instead of spending a hefty amount on doggy dental.
  • Many vets recommend this toothpaste because the enzymatic formula cleans plaque right off the dog’s teeth.


  • A few customers said the vanilla mint flavor leaves a slightly minty odor behind but their dogs didn’t mind it.
  • A few customers said they wish the opening of the toothpaste bottle is a little smaller. The opening is wide and shoots out more toothpaste than needed.

Our Best Budget Pick: Sentry Petrodex Enzymatic Toothpaste For Dogs

The Sentry Petrodex Enzymatic Toothpaste For Dogs is an affordable and popular choice amongst pet owners. At such a budget-friendly price, you’ll be pleasantly surprised by its cleaning power. The 6.2-ounce Petrodex Enzymatic toothpaste for dogs contains patented enzymes that remove plaque and control tartar formation. The enzymatic formula removes the most stubborn plaque and tartar.

All the while, the non-foaming formula means the teeth brushing routine is easier and painless since there is no need to rinse and leaves your dog with fresh breath.

Let’s not forget the poultry flavor in the Petrodex Enzymatic toothpaste. It is one of the most palatable flavors that the majority of dogs love. Your dogs will love it too. For the best result, add the Petrodex dog toothpaste onto a soft-bristled toothbrush or a finger brush.

Sentry Petrodex Enzymatic Toothpaste For Dogs Key Features:

  • Petrodex enzymatic toothpaste reduces plaque and control tartar formation to prevent gum disease
  • Patented enzymes with non-foaming formula gently clean without the need to rinse
  • Get rid of bad breath with regular use
  • Palatable poultry flavor your dogs will love

What customers are saying:  


  • After just a short period of usage, some owners noticed the toothpaste soften and loosen the tartar around their dog’s teeth.
  • Dogs love the taste of the toothpaste which makes teeth brushing a breeze!
  • Many pet owners recommend brushing your dog’s teeth daily to prevent pain and oral health issues.
  • Dog owners noted that the tube lasted more than a few months even when it’s used daily.
  • Many dogs would not go to bed until their teeth is brushed.
  • One particular owner uses Sentry dog toothpaste for more than 20 years and hasn’t yet been disappointed.


  • Although some customers said the toothpaste stinks, their dogs love it and that’s what matters.

Best Vet Recommended Dog Toothpaste: Vet’s Best Dental Gel Toothpaste

If you’re looking for a vet-recommended toothpaste, look no further than the Vet’s Best Dental Gel Toothpaste.

This veterinarian formulated toothpaste contains an effective mix of natural ingredients such as aloe, neem oil, grapefruit seed extract, and enzymes. Neem oil helps improve your dog’s oral health. These ingredients have both antibacterial and antifungal qualities that are tough on plaque, tartar, and bacteria while gentle on your dogs’ teeth, gum, and tongue.

In no time, your canine companions will have cleaner and whiter teeth with little to no plaque and their tartar will be under control. Recommended for daily use, your dog will love its natural flavor.

There are three ways to apply the Vet’s Best toothpaste. First, you can apply a dab of toothpaste directly on your dog’s tongue to instantly freshen their breath. Second, you can squeeze a bit of toothpaste onto your finger and brush your dogs’ teeth (if you’re comfortable). Third, you could apply the toothpaste onto a toothbrush with a soft bristle.

The Vet’s Best Toothpaste supports your dog’s dental hygiene between annual cleanings at the vet’s office.

Vet’s Best Dental Gel Toothpaste Key Features:

  • Veterinarian formulated toothpaste containing natural ingredients
  • Effective and soothing ingredients have antibacterial and antifungal qualities
  • Remove plaque, control tartar formation and freshens breath
  • Great for in-between annual cleanings at the vet’s office

What customers are saying:  


  • Many dogs love the taste of the Vet’s Best toothpaste – even pups that never had their teeth brushed before.
  • Pet owners were amazed to see the results after using it for a month. The natural ingredients in the toothpaste help soften and loosen the tartar.
  • A lot of dog owners noted the following: toothpaste soothes their dogs’ irritated teeth and gums, helps eliminate tartar buildup and improves their dogs’ bad breath.


  • A few customers said the toothpaste isn’t minty enough but their dogs love it.
  • The Vet’s Best dental gel is runnier than your typical toothpaste so try not to squeeze the tube too fast.

Best Organic Dog Toothpaste: RADIUS USDA Organic Toothpaste

The RADIUS USDA Organic Toothpaste is our best organic dog toothpaste. The USDA organic toothpaste cleanses your dogs’ teeth and helps to reduce bacteria, prevent tooth decay, and freshen breath.

The Radius organic coconut oil toothpaste also comes with a firm toothbrush. Together, the toothpaste and toothbrush help to remove plaque, prevent tartar and soothe the gum.

The toothpaste doesn’t contain xylitol, chemicals, preservatives, dyes, pesticides, GMOs, gluten, fluoride, saccharin, or artificial additives. Instead, it only contains organic food-grade ingredients such as organic coconut oil, sweet potato, and cinnamon so your canines are free from harmful ingredients.

RADIUS USDA Organic Toothpaste Key Features:

  • Made with organic, food-grade ingredients
  • Non-toxic: no xylitol, chemicals, preservatives, dyes, pesticides, GMOs, gluten, fluoride, saccharin, artificial additives, sweeteners, or flavors
  • Cruelty-free, Latex-free, SLS and SLES free, BPA-free, and BPS-free
  • Firm bristles to remove tartar, control plaque formation, and clean gums
  • Freshens breath
  • Made in the USA
  • Comes in Adult Kit, Puppy Kit, Senior Kit, or just the 3 oz Toothpaste

What customers are saying:  


  • Many pet owners said the toothbrush is easy to use. They prefer the toothbrush over the finger brush.
  • After using this toothpaste, dog owners happily noticed their dogs’ teeth are cleaner and whiter with healthy gums.
  • Some dogs are picky when it comes to flavors, yet they enjoy the natural taste of RADIUS organic toothpaste. They also seem to love the smell..
  • A few dog owners commented that they are happy there’s an organic toothpaste that isn’t meat or poultry flavored.


  • A few customers did not like the color of the toothpaste, but that it works great overall.

Who Should Buy Dog Toothpaste

Every dog owner should invest in a good quality dog toothpaste because routine teeth cleaning is vital to maintain good oral hygiene in dogs. If your pups do not like getting their teeth cleaned, you should still invest in dog toothpaste. In case of a dental emergency, you’ll be glad you had one laying around.

While all dogs need to have their teeth cleaned, it’s important to note that some dogs benefit from regular cleaning more than others.

For instance, dogs with squished noses often have teeth that are closer together. Things can get stuck in the teeth which can lead to tartar build-up or gum disease. If your dog has this feature, use a good quality toothpaste and brush their teeth regularly.

Make sure your pups still get their annual dental cleaning. At-home teeth cleaning should not replace dental cleaning at the vet’s office. It’s a way to maintain good oral hygiene in between dental cleanings and checkups.

Key Features to Consider

When selecting dog toothpaste, it is helpful to know a list of key features to look out for. Below, we’ve listed a few key features that will help guide you in finding the best toothpaste for your furry friends.

  • Cleaning power. The first feature of any dog toothpaste is its cleaning power. It should be able to clean your dogs’ teeth and gum to remove plaque, soften and remove tartar build-up, and get rid of bacteria. A high-quality dog toothpaste will contain an enzymatic formula that can remove even the most stubborn caked-on tartar and plaque. This is helpful if you’ve just started an oral hygiene routine for your dogs, but was lax about it in the past.
  • Enzymatic formula. Many dog toothpaste, including the ones we recommend above, contains an enzymatic formula. Dog toothpaste that contains enzymatic formula helps to effectively remove and prevent plaque, control tartar formation, polishes your dogs’ teeth and freshens their breath.
  • Non-foaming formula. Always choose a dog toothpaste that contains a non-foaming formula because the toothpaste is safe for dogs to swallow and does not require the need for rinsing. This means brushing your dogs’ teeth will be quicker and easier. Many dog toothpaste contains a non-foaming formula, but not all so it’s always best to check and make sure.
  • Palatability and flavor. Many dog owners love that dog toothpaste has palatable flavors in order to attract or convince their furry friends to get their teeth brushed. In fact, many dogs love the palatable favors in the doggy toothpaste so much that they will head over to their owners and wait for their teeth to be brushed before bedtime. Dog toothpaste can come in palatable flavors including poultry, beef, and vanilla mint. However, be aware that not all of the toothpaste is equally tasty. Some flavors that may be palatable and tasty to some dogs may not be palatable or tasty for your dogs. Knowing which flavor your canine friends love is helpful in selecting the best toothpaste for them. When your dogs love the flavor of the toothpaste, they will likely be distracted by the taste and would not mind getting their teeth brushed. Make sure your dogs love the taste because if they don’t like it, the teeth brushing routine may take longer and become a headache.
  • Tube size. When comparing toothpaste and the price, take a look at the tube size as well. For instance, toothpaste X might cost $2 more than toothpaste Y, but if toothpaste X is a 7-ounce tube while toothpaste Y is a 4.5-ounce tube, then toothpaste X is a better value for your money.

How to Soften Dog Tartar

Tartar can get quite hard so it’s always best to control tartar formation before they become hard on your dogs’ teeth. After brushing your dogs’ teeth with the enzymatic toothpaste listed above, you’ll start to notice the tartar softening. Once the tartar softens, it’s easier for it to break down.

Brushing Dog’s Teeth With Baking Soda?

It is not safe to brush your dogs’ teeth with just baking soda. Baking soda contains high alkaline content. If swallowed, it can upset the acid balance in their stomach and digestive tract. Not only that, brushing with just baking soda does not taste good. Your dogs may be uncooperative with the unpleasant taste and it will also take longer to brush their teeth.


What is the Difference Between Dog Toothpaste and Human Toothpaste? Can You Use Human Toothpaste On Dogs?

One of the main differences between dog toothpaste and human toothpaste is that the toothpaste designed for dogs can be safely swallowed, while the human toothpaste is not designed to be swallowed and has to be rinsed out of the mouth. Another difference is that some dog toothpaste has non-foaming agents while human toothpaste will foam when activated. The most important difference between human toothpaste and dog toothpaste is that the human toothpaste usually contains ingredients that are very toxic to dogs, such as the sweetener xylitol. Dog toothpaste is designed specifically for dogs to ensure it is safe for them to use. Please avoid using human toothpaste to brush your dogs’ teeth at all costs.

What Is Enzymatic Toothpaste For Dogs?

Dog toothpaste with enzymatic formula is crucial for dogs. If you have an enzymatic dog toothpaste, it contains either the enzyme glucose oxidase (GOx) or both GOx and lactoperoxidase (LPO).

When GOx is exposed to glucose and oxygen, it becomes antibacterial and generates hydrogen peroxide that helps get rid of plaque and control tartar formation.

The hydrogen peroxide then activates the LPO which also gets rid of plaque. When the enzymes come into contact with your dogs’ teeth, they begin working immediately.

This is perfect since dogs usually have very low patience with teeth brushing or hate long teeth brushing sessions.

When Should I Start Brushing My Puppies’ Teeth?

It is always best to start the dog teeth brushing routine early. After your puppies settle in and get acclimated to your house, you can begin to get them on a brushing routine. It is ideal to start this process when your puppies are between 8 to 16 weeks of age. Start slowly. During the teeth brushing process, give plenty of praises and treats so they can associate the routine with food and fun. This will get them acclimated to the teeth brushing process early. Starting early also makes your job easier. By the time your furry friends reach adulthood, they already know the teeth brushing routine and it will become second nature to them, just like mealtime and potty time.

How Often Should Dogs Get Their Teeth Cleaned?

We recommend brushing your dog’s teeth daily or 1-2 times per week. We understand this sounds crazy and it’s a job most owners dread but brushing your dog’s teeth every day is best because plaque builds up after 48 hours. However, like many owners, you can resort to brushing your dog’s teeth at least a few times every week, which is better than nothing. This will help your dog maintain proper oral hygiene and avoid emergency veterinary dental procedures, which can take an unexpected toll on your wallet.

Other Dog Toothpastes We Reviewed

We’ve also reviewed the following dog toothpaste and included the product information for your convenience.

  • Best All Natural Dog Toothpaste
  • Best Dog Toothpaste For Bad Breath
  • Best Enzymatic Dog Toothpaste
  • Best Puppy Toothpaste

Best All Natural Dog Toothpaste

The TropiClean Fresh Breath for Dogs is made of a natural blend of unique ingredients including spearmint, glycerin, and green tea leaf extract that get rids of plaque, tartar, and bacteria that causes bad breath, yet gentle on your dogs. No brushing is required. You simply apply two drops of TropiClean Clean Teeth Gel to each side of your dog’s mouth daily. This helps remove plaque and tartar safely and effectively.

TropiClean Fresh Breath for Dogs Key Features:

  • No added sweeteners or sorbitol
  • Remove plaque and tartar buildup resulting in cleaner teeth
  • Formulated with a unique blend of ingredients including green tea leaf extract
  • Remove bacteria for fresher breath
  • No brushing required
  • Made in the USA
  • For dogs 12 weeks and older

What customers are saying:  


✅ Many dog owners can’t believe the incredible result from this product. Within two weeks, they noticed that most of the tartar went away. When they brought their furry friends to the vet for dental checkup, their vets also couldn’t believe it and decided to look into it.

✅ Dog owners love that this gel smells like sweet spearmint, one of the natural ingredients in the toothpaste and their dogs love it. They noted that most toothpastes are meat or vanilla flavored, which makes their dogs’ breath even worse, but the spearmint flavor in this product helped freshen their breath.

✅ Some dog owners have dogs with mild to severe tartar. After about a month of applying this product, the mild tartar came right off and their dogs with severe tartar showed great improvement. Some owners mentioned that using the gel will save them hundreds in vet bill.

✅ A lot of owners love that there is no brushing required. They just apply two drops of the product to each side and within days, chucks of tartar fell off their dogs’ teeth.


❌ Some dog owners noted that you really have to use this product daily, if not twice a week for the results to show. You have to remember to do it or note it down on your calendar. When it’s applied daily, the gel works magic and removes even the most solid plaque.

Best Dog Toothpaste For Bad Breath

The Arm and Hammer Dental Care Toothpaste is gentle yet effective in maintaining your dog’s oral hygiene. The toothpaste is made with natural ingredients so your dog will love the flavor such as chicken or beef while maintaining good dental health.

Using the dental kit will help to reduce tartar buildup, clean your dog’s teeth, and eliminate bad breath. The dental kit includes both toothpaste and a toothbrush. If you have puppies or have just adopted a new dog, using the toothbrush is a good idea.

Purchasing this set will also save you time from having to choose a toothbrush to use with the toothpaste.

The toothpaste helps to eliminate bad bacteria that cause bad breath, control tartar formation, and get rid of plaque. The kit also comes with instructions to make it easier for you to introduce your furry friends to get their teeth brushed.

If you’re a first-time brusher, wrap a gauze or washcloth around your finger. Then, put a small amount of toothpaste on it and invite your dog to lick it off. This way, she will get familiar with it. Next, slowly progress to rubbing your finger (wrapped with gauze or washcloth) along your dog’s gum line and teeth.

Arm and Hammer Dental Care Toothpaste Key Features:

  • Comes in 1 Pack, 2 Pack and Puppy Training Kit
  • Get rid of bad breath, plaque, and tartar
  • Available style: Fresh Breath – Chicken, Tartar Control – Beef, Fresh Breath – Vanilla Ginger, Gum Health – Chicken, Tartar Control – Banana Mint
  • The dental kit is safe, gentle, and suitable for all dogs and puppies

What customers are saying:  


✅ The majority of the owners said they were first-time brushers. After using this dental kit on their dog’s teeth and gum and realizing how easy it is, they highly recommended this dental kit for first-timers.

✅ Many owners advised starting slow and slowly introducing the toothpaste and brush. The whole process will take a few days and it is best to be patient. After using the dental kit for a week, they noticed the difference in their dog’s breath and teeth.

✅ Some owners were happily surprised that the toothpaste actually whitens their dog’s teeth. Although the owners were not a fan of the flavor smell, their dogs loved the flavor.

✅ Owners also noticed that the finger brush works best over the toothbrush, but this is a matter of preferences than the product itself.


❌ 1-2 customers said either their dogs loved the toothpaste and hated the brush or loved the brush and hated the toothpaste. It’s all a matter of their dog’s preference.

Best Enzymatic Dog Toothpaste

If none of the enzymatic toothpaste above suits your dogs’ needs, you can also use the Vetoquinol Enzadent Enzymatic Toothpaste. The tasty poultry-flavored toothpaste attracts and distracts your dogs while they are getting their teeth brushed.

With its triple enzyme formula, the toothpaste breaks down food debris and plaque, leaving your canine friends with clean, polished, and healthy teeth.

The non-foaming toothpaste makes the teeth cleaning process easier since no rinsing is required and it can be safely swallowed.

Best of all, your pooch will be left with a fresh breath since the ingredients in the toothpaste combat harmful bacteria that causes bad breath.

Vetoquinol Enzadent Enzymatic Toothpaste Key Features:

  • Tasty poultry-flavored enzymatic toothpaste
  • Triple enzyme formula removes plaque, control tartar and freshens breath
  • Non-foaming and safe to swallow
  • Improves oral hygiene

What customers are saying:  


✅ Dog owners noted that their canines that usually hate toothpaste and teeth cleaning actually loves this toothpaste after using it. They advised starting slow and brushing just a few seconds at a time in the beginning. Then, increase the length of teeth brushing once your dogs are more comfortable. They recommend the poultry flavor as this is the flavor that their dogs love.

✅ After a week of using this toothpaste, dog owners noticed the plaque started to go away. After about a month, they saw the huge improvement in their teeth appearance.

✅ Owners with dogs that have really bad teeth to begin with started using this product and saw their dogs’ teeth getting cleaner and whiter. This toothpaste helped them remove 90% of the tartar in their dogs’ teeth and cured their irritated gums.


❌ One customer noted that the toothpaste is watery and some would drip to the floor when they try to apply it to the tooth brush. *This was the only mention of watery toothpaste. None of the other reviews mentioned the toothpaste being watery.*

Best Puppy Toothpaste

The Radius USDA Organic Toothpaste Puppy Kit comes with a toothbrush that is designed for puppies. The toothbrush has premium ultra-soft bristles that gently clean your puppies’ teeth and massage their delicate gum tissues. The toothpaste is USDA certified and organic. It does not contain any synthetic foaming agents, detergents, or artificial additives. Early prevention is key. By brushing their teeth at a young age, you’ll help them prevent plaque and tartar. Best of all, the toothpaste helps freshen their breath. Made in the USA, we believe this toothpaste and soft toothbrush set is the perfect introduction to teeth brushing for your cute little puppies.  

Radius USDA Organic Toothpaste Puppy Kit Key Features:

  • Recommended for puppies age 0-18 months
  • USDA certified and organic: no synthetic foaming agents, detergents, or artificial additives
  • The toothbrush has premium ultra-soft bristles
  • Remove plaque and tartar and freshen breath
  • Made in the USA

What customers are saying:  


✅ Many dog owners with puppies said their puppies love this toothpaste. Out of all the puppy grooming routines, their puppies love teeth brushing and it’s one of their favorite activities to do. Best of all, they love the taste and smell of the toothpaste. It smells like cinnamon and cloves with a dash of meat flavoring. The owners found the soft bristle toothbrush to be helpful and easy to brush.

✅ A lot of owners said their puppies love the toothpaste and the brush is very soft on their teeth as well as their gums. The natural ingredients in the toothpaste are exactly what they were looking for. They would buy it again.

✅ The teeth brushing routine with this product is stress-free for both the puppies and the owners. When their puppies see them getting ready to brush their teeth, they would wag their tails and can hardly wait to get started.


❌ Two customers prefer to use the finger toothbrush for their puppies. It’s a matter of each owner’s preference for their puppies.